Chapter 195 Artemisinin and Artemisinin Powder

The fourth day of the Lunar New Year.

Saturday.

Early in the morning, Wang Mengde got up from bed and woke up his two sons from their sleep.

The three of them first got ready in the bedroom and exercised for about half an hour.

Of course, he developed this habit since he was a child, and doing a few rounds of boxing every day has become a habit.

No matter how busy he is, he will always find time to exercise. He will feel uncomfortable if he doesn't exercise for a day.

The two children, on the other hand, yawned continuously, looked weak and sleepy, and could only copy what others had done.

Wang Mengde didn't care. He just needed to develop a habit now. With more practice, his movements would naturally become standardized.

After practicing boxing, he took out an ointment and applied it on the ears of Wang Yuanxun and Wang Yuandi.

In this day and age, because there are insufficient warming measures and no heating, children all like to have fun outside.

So, in winter, basically every child will have frostbite.

It is most likely to appear on the ears, back of the hands and face.

Even among the children in Wang Mengde's family, except Yaya who is well protected, the other four suffer from frostbite to varying degrees every year.

Once frostbite occurs, you will feel very itchy in your warm bed at night. If you scratch it with your hands, pus will flow out, and the more you scratch, the more itchy it will become.

In the end, a vicious cycle is formed, the area of ​​frostbite becomes larger and larger, and scars are likely to be left.

For the sake of his family's children, Wang Mengde spent some time and effort to prepare an ointment last year.

This ointment can prevent frostbite, protect the skin, and relieve itching.

After applying this ointment regularly, the children have not had frostbite this year.

After applying the medicine, the three of them carried washbasins and toiletries and came to the pool in the middle courtyard to line up for washing.

"Wow, Yuanxun and Yuandi got up so early."

They were lining up when Liu Haizhong staggered over from the backyard and came behind them.

In the past two years, there has been a shortage of supplies on the market, insufficient rations, and lack of nutrition.

Especially since last year, for about a year, we could only eat meat once or twice a month. Because of the supply shortage of eggs, we only ate scrambled eggs two or three times a year.

Fortunately, several people in his family have Beijing household registration, and he is a fitter, which involves heavy physical labor, so the workload is higher than that of ordinary people.

With a monthly salary of eighty or ninety yuan, I can barely eat enough every day.

But even so, he has lost at least two times less weight, he doesn't even have a belly anymore, and he is not as fat as in the original drama.

Now he looks just a little stouter than the average person.

"Master!"

The two children shouted crisply.

"Uncle, they are used to getting up early."

Wang Mengde explained.

"This is a good habit. Unlike my two boys, they haven't gotten up yet."

Liu Haizhong praised with a smile.

At the same time, seeing the four or five-year-old children getting up so early, the comparison made me feel disgusted with the two unfortunate children, Liu Guangtian and Liu Guangfu.

After washing up, I beat my two sons first and then had breakfast.

After brushing their teeth with tooth powder, Wang Mengde took a basin of water and carefully washed the brothers' faces.

Fortunately, the water pumped from the pressurized well is not too cold in winter.

arrive home.

Breakfast was ready.

At the dinner table, He Shengnan first peeled a boiled egg and then put it directly into Wang Mengde's porridge bowl.

Then he started to peel eggs for his daughter.

As for the two sons, they are grown up and need to provide for themselves.

"Shengnan, I don't eat eggs. I'll give this to you."

Wang Mengde picked up the bowl and was about to transfer the eggs in the bowl to his wife's bowl.

He usually seems to eat and drink the same way as his family, but in fact he often secretly takes out some fruits, snacks and food from his previous life from the space to satisfy his cravings.

If he had not practiced martial arts for many years and consumed a lot of energy, he would definitely have become a very rare fat man in this era.

"No, you can eat it. I have some too."

He Shengnan said with a smile while peeling eggs and shielding her bowl with her arm.

She felt very sweet and enjoyed the care from her man.

"Meng De, please eat. I cooked nine eggs today, just one for each person."

On the side, Ran Xiaomei also said with a smile.

Today is still the Chinese New Year, and it is also the first day of work in the new year, so she was very extravagant and cooked a few more eggs.

Under normal circumstances, I would cook one for each of my children.

"Okay, I'll eat it then."

As he spoke, Wang Mengde used chopsticks to break the egg white and split the yolk in half, then put them into the bowls of Wang Yuanxun and Wang Yuandi respectively.

The two brothers didn't hesitate and accepted it happily.

After breakfast.

Ran Xiaomei carefully placed all the egg shells on the dining table into the stove in the corner of the living room, and they were soon burned to ashes.

I can't let others see me eating such an egg for a meal.

Otherwise, if he was reported, even if many leaders of the street and neighborhood committee were comrades who had fought side by side with Lao Wang in the past, his son would still be very powerful.

It's not a good thing either.

Maybe it will affect my son.

After all, everyone is short of food and clothing, but our family eats so well.

Chinese Medical Research Institute.

Wang Mengde sat on a chair in his office, looking at the ten energetic people in front of him, and said with a smile:

"Haha, I wish everyone a happy new year."

"Brother, we also wish you a happy old age."

"Yes, Director Wang, I will also give you a good old age."

Several junior fellow students, Qian Dayong and others also spoke hurriedly.

After a lively moment, when everyone's emotions had calmed down, Wang Mengde began to talk about the issues he had thought of before the New Year.

"The other day I was inspired by the sentence 'Take a handful of Artemisia annua, soak it in two liters of water, squeeze out the juice, and drink it all' in Ge Hong's book 'Emergency Prescriptions for Treating Cold, Fever and Malaria' from the Eastern Jin Dynasty.

We believe that the Artemisia annua samples we provided may have damaged their active ingredients due to high temperature, thus affecting the test results.

So, we will change the extraction of Artemisia annua from ethanol to ether, which has a lower boiling point than ethanol. This needs to be done as soon as possible, and we will try to send it for inspection in the next two days."

After briefly stating his thoughts, he looked at everyone.

"What do you think?"

"We have no problem with that."

Qian Dayong and the others naturally had no objections and thought what he said made a lot of sense.

In fact, if Wang Mengde hadn't spoken yet, they would have been eager to go to the laboratory immediately.

"Okay, since you have no objection, let's go to the laboratory first, extract the Artemisia annua sample, and send it for testing as soon as possible."

Wang Mengde instructed. Three days later.

After their overtime experiments and with the strong cooperation of the Academy of Military Medical Sciences.

Finally, good news came.

After receiving the test report and seeing the words 'This sample has 100% inhibition rate against malaria virus' written on the top, Wang Mengde was very excited.

Today, their research has taken a big step forward.

And it is the most critical step.

With this report, he can combine Artemisia annua with other Chinese herbal medicines based on its characteristics.

Most importantly, he learned how to use Artemisia annua.

That is, it cannot be used directly as medicine by decocting in water.

This is very critical.

If you don't know, once you carry out the conventional water decoction operation, the medicinal effects of Artemisia annua will be lost completely and become completely ineffective.

Thinking of this, Wang Mengde asked them to continue some extraction experiments and re-extract the previously screened prescriptions and Chinese herbal medicines with ether.

This is not aimless. Sometimes, there may be surprises waiting for you.

He was flipping through medical books while thinking about how to formulate the prescription.

Time passes day by day.

Soon, after eating Yuanxiao, the Mid-Autumn Festival was over, and this Chinese New Year was completely over.

Every household began to live a more difficult life.

Not only do ordinary families not have enough food to eat, but even factories and units are tightening their belts.

Shazhu hasn't brought back a lunch box for several days.

It’s not that he doesn’t want to bring them, but the leaders in the factory don’t dare to prepare special meals for guests.

Nowadays, almost all working families have cases of hunger every month.

At this time, if they continue to eat and drink without any scruples, the workers will let them taste the power of class.

Everyone on the street looked thin, and they all tightened their belts again and again.

Anything that can be eaten will not escape the sharp eyes of the public.

Wang Mengde's family became more cautious when eating.

The children were repeatedly reminded not to mention any food situation at home outside.

this day.

In Mr. Pu’s office.

When Wang Mengde handed him several prescriptions, Pu Lao looked at them for a long time before asking in disbelief, "Mengde, is this the prescription you developed to treat malaria?

Why don't you boil the Artemisia annua together with the other herbs, but use other methods to extract the juice first, and then add it in after the other herbs are boiled?"

He didn't shy away from asking about the strange things inside.

"Sir, it's like this. I extracted and tested it today and found that Artemisia annua cannot withstand high temperatures. Once it is exposed to high temperatures, the efficacy of the medicine in treating malaria will completely disappear."

Wang Mengde briefly talked about the research he had done recently.

"So that's it!"

Pu Lao suddenly realized: "No wonder I used Artemisia annua as medicine before, but the effect was very mediocre. It turns out that after conventional water decoction, it has no effect."

Before he came to Beijing, he practiced medicine in Sichuan for many years and had seen a lot of cases of diseases such as malaria.

There are dozens of prescriptions, whether they are ancient recipes or self-developed prescriptions, and basically all of them use Artemisia annua.

As for the final effect, it can only be said that it is not ideal. Many patients rely entirely on their own immunity to fight the disease.

He didn't know the reason before, but now through his disciples' explanation, he finally discovered the problem.

"Okay, Meng De, if your prescription is effective, it will be a great blessing for the people in the south."

Pu Lao said happily.

As a southerner, he can relate to the hot climate, which makes it particularly prone to the breeding of some infectious diseases.

I just regret that my abilities are limited and I am powerless to treat many diseases.

Now, as a disciple, I am constantly overcoming some difficult and complicated diseases.

He believes that as Wang Mengde continues to grow, more difficult diseases will be transformed from incurable diseases into common illnesses.

After looking at several prescriptions again and again, Pu Lao stood up happily and said with a smile: "Let's go, I will go with you to see the dean. I believe he will be very excited when he hears the news."

Ten minutes later.

Holding a few prescriptions, Dean Lu widened his eyes, his face full of surprise.

"Wow, right after the Chinese New Year, there's already a surprise, and it's such a big surprise."

Without even verifying the effectiveness of these prescriptions, he arbitrarily concluded that they would definitely be effective.

And the effect will be very good.

This is the result of Wang Mengde's efforts in recent years, which gives him confidence.

"Dean, these prescriptions have not been verified yet. I think it would be better to conduct clinical trials first."

Wang Mengde spoke hurriedly.

He was really afraid that the dean would get carried away and directly treat these prescriptions as test prescriptions.

After all, although he had a rough idea in his mind, he still had to be cautious.

"Well, I have to go to my superiors for a meeting this afternoon, so I can report this matter to them.

By the way, please tell me the details of your research. The more detailed the better."

After saying that, he stretched his neck with interest, looking forward to Wang Mengde's story.

Seeing his look, Wang Mengde had no choice but to repeat what he had just said to Pu Lao.

Finally, he added, "The research we are doing this time is not only helpful for these prescriptions, but can also be directly developed into Western medicine for the treatment of malaria."

"What? Can it be directly developed into Western medicine?"

Dean Lu asked with a look of surprise.

"Yes, the Artemisia annua samples we extracted have been tested and found to have a very high inhibition rate against malaria virus. They can definitely be developed into Western medicine."

Wang Mengde said affirmatively.

In the past, artemisinin was the active ingredient obtained from Artemisia annua through extraction, separation and other techniques.

However, the specific steps were kept secret by the state, and he could only get a general idea from the space.

"However, we are short of manpower, and we are not familiar with the development of Western medicine, so we may not have the time and energy to study it."

Seeing that Dean Lu looked interested, Wang Mengde added.

After receiving Wang Mengde's affirmative answer, Dean Lu did not take his supplement to heart, but said proudly:
"Comrade Wang Mengde, don't worry. There are many doctors in the institute who are very good at Western medicine. It's just right to let them take over and continue the research."

After saying this, he thought to himself that if the Chinese Medical Research Institute could research effective medicines in both Chinese and Western medicine, he would be able to stand out in front of his superiors.

Didn't make him wait any longer.

Soon, the superiors took action.

Hainan was directly selected as the clinical trial base, and some researchers were sent to the base for on-site observation.

Considering that Wang Mengde had other research tasks to complete and could not leave, he selected three of his fellow junior and senior classmates to go.

Half a month later, Zhang Qiaoyu came to Wang Mengde's office panting.

She said excitedly: "Brother, Brother Li Xiang called and it's about the clinical trial results of Qinghaosan."

(End of this chapter)